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Triggers of Neuroinflammation in Autism: Gut Dysbiosis and Immune Dysregulation

alexaautism

One of the key triggers of neuroinflammation in autism is gut dysbiosis, which disrupts the maturation of the immune system. A healthy gut is critical for educating the immune system, but when dysbiosis occurs, it leads to immune dysregulation. This dysregulation causes an imbalance between pro-inflammatory and anti-inflammatory responses, resulting in chronic inflammation. This inflammation often spreads beyond the gut, activating microglia, the immune cells of the brain. Activated microglia release cytokines and inflammatory molecules, which contribute to cognitive, behavioral, and sensory difficulties in children with autism.To combat this, addressing gut health is paramount. A gut-healing protocol—including the removal of food intolerances (e.g., gluten and dairy), the introduction of anti-inflammatory foods, and supplementation with probiotics—can help restore gut microbiome balance and reduce neuroinflammation. Supporting immune health by avoiding environmental toxins and reducing inflammatory triggers is also crucial.

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